Установлено точное наследование риджа Опции

[Nana]

We have just learned that the specific genetic mutation responsible for the ridge in the Rhodesian Ridgeback has been found.

The work was done by Dr. Leif Andersson at Uppsala University in Sweden in collaboration with researchers at the Broad Institute/MIT here in the U.S. and the Swedish University of Agricultural Sciences. A paper will be published in the coming months, and Dr. Andersson expects a genetic marker test to be available in the fall, pending licensure, etc.

That is all the information Dr. Andersson has given us, along with his permission to disclose it to the Ridgeback community. We know you are as thrilled as we are.

As many of you know, Dr. Mark Neff, in collaboration with RRCUS, was also searching in parallel for the same marker. While Dr. Neff's efforts were not responsible for this discovery, we all agree it is wonderful for the breed.

We are sure this will be a subject of intense interest at Dr. Bell's seminar next Wednesday at the National Specialty in Ohio, as he will be discussing the implications of a direct-marker test for breeders.
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Коротко:
Сотрудничество шведов и американцев привело к тому, что 23 мая на семинаре в Америке на Национальной выставке в Охайо будет объявлено о точном наследовании риджа и маркеровочных тестах. способных определить носителей. И т.д.

[Nana]

Добавлю из ссылки:
http://www.nature.com/ng/journal/vaop/ncur.../ng.2007.4.html

The dorsal hair ridge in Rhodesian and Thai Ridgeback dogs is caused by a dominant mutation that also predisposes to the congenital developmental disorder dermoid sinus. Here we show that the causative mutation is a 133-kb duplication involving three fibroblast growth factor (FGF) genes. FGFs play a crucial role in development, suggesting that the ridge and dermoid sinus are caused by dysregulation of one or more of the three FGF genes during development.
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Мутация под названием "ридж" в РР и тайцах является причиной ДС. В этот признак вовлечены три гена отвечающие за фактор роста фибробластов, неправильное функционирование один или более из которых в процессе развития зародыша и являются причиной риджа и ДС.



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От себя: ради бога извините за некорректный перевод генетических терминов.... Я - не генетик.